Every Gene Has an Island

■ Life Sciences / Every Gene Has an Island “Islands” of cytosine-phosphate-guanine repeats in genes are modified differently depending on cell type, leading to cell type-specific gene expression. A team from Yonsei University, led by Dr. Young-Joon Kim, have uncovered a novel regulatory mechanism of cell differentiation involving intragenic CpG islands (iCGIs), stretches of cytosine-phosphate-guanine (amino acid) repeats located throughout the genome. Our bodies’ diverse cells begin as embryonic stem cells containing numerous genes that will subsequently be either expressed or repressed, depending on what cell type the gene winds up in. Much of a gene’s activation or suppression is dependent on so-called epigenetic processes … Continue reading Every Gene Has an IslandRead More →